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Treatment of Guillain-Barre Syndrome with High-Dose Immune Globulins-Combined with Methylprednisolone:Dutch Guillain-Barre Study Group Ann Neurol 35:749-752, , 1994 See this aricle in Pubmed Article Abstract In an open study 25 patients with Guillain-Barre syndrome were treated for 5 days with intravenous immune globulins in a dose of 0.4 gm/kg of body weight/day and 0.5 gm of methylprednisolone intravenously per day.The results of this combined treatment were compared with the results from a group of 74 patients who were treated with immune globulins only in a recent immune globulin treatment group,19 of 25 patients(76%)improved by one or more functional grades after 4 weeks,as compared with 39(53%)of 74 patients treated with immune globulin alone(p=0/04).Also,the median time required to the stage of walking independently was reduced in the methylprednisolone immune globulin treatment group.This pilot study suggests that combined treatment with methylprednisolone and immune globulins in patients with Guillain-Barre syndrome is more effective than treatment with immune globulins alone;a randomized clinical trial might confirm this.

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(click to filter results - removes previous filter) gammaglobulin therapy,intravenous Guillain Barre syndrome Guillain Barre syndrome,steroid treatment in steroid steroid therapy,CNS treatment and complications with treatment of neurologic disorder

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